Some keys get used more just because they’re more common, but for keyboard fiends, there’s a whole different set of keys that get worn out. If you’ve ever worn out the ⌘, Ctrl, or alt keys on your keyboard, chances are you couldn’t get by with just a mouse.
If anything, keyboard shortcuts are one of the best things in OS X. There’s the usual suspects, like ⌘+C and ⌘+V for copy and paste, or ⌘+tab for switching between apps, but you get those everywhere. Then there’s the ones that make OS X especially nice for writing: Alt+left/right to jump between words and ⌘+left/right to jump to the beginning/end of a line, with the addition of holding shift down to select text. There’s even more obscure text editing shortcuts, like Ctrl+T to swap the two letters your curser’s currently between.
Then, there’s the even more powerful keyboard shortcuts: those like ⌘+space to open Spotlight search or the default Alt+space to start Alfred. Those — combined with app specific shortcuts, and those you can setup yourself from your Keyboard’s system preferences — are the most powerful tools to keep you from having to revert to your mouse or touchpad all day. They’ll get so ingrained in your muscle memory, a computer without them feels broken.
For me, Alt+space is that killer shortcut that I invoke over a hundred times a day to use Alfred. What’s your favorite keyboard shortcut?